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Research Highlights
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Under the leadership of Dr. Tak Mak, The Campbell Family Institute has made great strides in a short period of time in the area of breast cancer research. Its key accomplishments include:
- Recruitment of an unparalleled team of scientific talent, including Dr. Pamela Ohashi, Dr. Hitoshi Okada, Dr. Norman Boyd, Dr. Lisa Martin, Dr. James Pan, Dr. Henry Pauls, Dr. Mark Clemons, Dr. Mona Gauthier and others
- Identification of a new therapeutic target: an enzyme that cancer cells need for survival when they are deprived of oxygen or nutrients
- Publication of a major finding in The New England Journal of Medicine by Dr. Norman Boyd on the significance of breast density as a risk factor – a globally significant discovery
- Development of mouse models which will play a critical role in identifying targets for new drugs
- Identification of several other genes or genetic regions that are selectively increased or decreased in breast cancer
- Establishment of The Campbell Family Drug Discovery and Development Team for developing new targeted cancer therapies
- Discovery of a new class of metabolic inhibitors with broad anti-cancer activity in animal models
- Discovery of proprietary kinase inhibitors with anti-cancer cell activity
- Establishment of collaborative relationships with Stanford, Johns Hopkins, Princeton, Washington University, UCSF, UBC and many other international organizations
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